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Sequence features of yeast and human core promoters that are predictive of maximal promoter activity

The core promoter is the region in which RNA polymerase II is recruited to the DNA and acts to initiate transcription, but the extent to which the core promoter sequence determines promoter activity levels is largely unknown. Here, we identified several base content and k-mer sequence features of th...

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Detalhes bibliográficos
Main Authors: Lubliner, Shai, Keren, Leeat, Segal, Eran
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3675475/
https://ncbi.nlm.nih.gov/pubmed/23599004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt256
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