Systematic Dissection of the Sequence Determinants of Gene 3’ End Mediated Expression Control

The 3’end genomic region encodes a wide range of regulatory process including mRNA stability, 3’ end processing and translation. Here, we systematically investigate the sequence determinants of 3’ end mediated expression control by measuring the effect of 13,000 designed 3’ end sequence variants on...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Shalem, Ophir, Sharon, Eilon, Lubliner, Shai, Regev, Ifat, Lotan-Pompan, Maya, Yakhini, Zohar, Segal, Eran
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4398552/
https://ncbi.nlm.nih.gov/pubmed/25875337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005147
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