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Differential Down- and Up-regulation of Rat Brain Opioid Receptor Types and Subtypes by Buprenorphine
The induction of opioid receptor adaptation by mixed agonist-antagonists such as buprenorphine has not been investigated. To this end, neonatal rats were given injections of buprenorphine (0.1-2.5 mg/kg/day) and μ binding (K(d) and B(max)) to brain membranes was measured with [(3)H][D-Ala(2),MePhe(4...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1993
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2516495/ https://ncbi.nlm.nih.gov/pubmed/8393519 |
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