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β-Endorphin Is a Potent Inhibitor of Thymidine Incorporation into DNA via μ- and κ-Opioid Receptors in Fetal Rat Brain Cell Aggregates in Culture
Thymidine incorporation into DNA was inhibited dose-dependently by β-endorphin in rat fetal brain cell aggregate cultures. The inhibition was reversed partially by μ (cyclic d-Phe-Cys-Tyr-d-Trp-Orn-Thr-Pen-Thr amide) or κ (norbinaltorphimine) antagonists. Complete blockade of the β-endorphin inhibit...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1993
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2571952/ https://ncbi.nlm.nih.gov/pubmed/8380443 |
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