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β-Endorphin Is a Potent Inhibitor of Thymidine Incorporation into DNA via μ- and κ-Opioid Receptors in Fetal Rat Brain Cell Aggregates in Culture

Thymidine incorporation into DNA was inhibited dose-dependently by β-endorphin in rat fetal brain cell aggregate cultures. The inhibition was reversed partially by μ (cyclic d-Phe-Cys-Tyr-d-Trp-Orn-Thr-Pen-Thr amide) or κ (norbinaltorphimine) antagonists. Complete blockade of the β-endorphin inhibit...

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Autores principales: Barg, Jacob, Belcheva, Mariana, McHale, Robert, Levy, Rivka, Vogel, Zvi, Coscia, Carmine J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 1993
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2571952/
https://ncbi.nlm.nih.gov/pubmed/8380443
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