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Differential Down- and Up-regulation of Rat Brain Opioid Receptor Types and Subtypes by Buprenorphine

The induction of opioid receptor adaptation by mixed agonist-antagonists such as buprenorphine has not been investigated. To this end, neonatal rats were given injections of buprenorphine (0.1-2.5 mg/kg/day) and μ binding (K(d) and B(max)) to brain membranes was measured with [(3)H][D-Ala(2),MePhe(4...

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Autors principals: BELCHEVA, MARIANA M., BARG, JACOB, McHALE, ROBERT J., DAWN, SAMUEL, HO, MATTHEW T., IGNATOVA, ELENA, COSCIA, CARMINE J.
Format: Artigo
Idioma:Inglês
Publicat: 1993
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2516495/
https://ncbi.nlm.nih.gov/pubmed/8393519
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