CpG methylation in exon 1 of transcription factor 4 increases with age in normal gastric mucosa and is associated with gene silencing in intestinal-type gastric cancers

Transcriptional factor 4 (TCF4), encoding a basic helix-loop-helix transcriptional factor, has recently been demonstrated as a causative gene for Pitt-Hopkins syndrome, a neurodevelopmental disease. Examination of gastric cancers using the restriction landmark genomic scanning technique revealed met...

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Hlavní autoři: Kim, Seung-Kyoon, Jang, Hay-Ran, Kim, Jeong-Hwan, Kim, Mirang, Noh, Seung-Moo, Song, Kyu-Sang, Kang, Gyeong Hoon, Kim, Hee Jin, Kim, Seon-Young, Yoo, Hyang-Sook, Kim, Yong Sung
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2008
Témata:
Carcinogenesis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2516490/
https://ncbi.nlm.nih.gov/pubmed/18635522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgn110
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