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Chemoprevention of dibenzo[a,l]pyrene transplacental carcinogenesis in mice born to mothers administered green tea: primary role of caffeine

Our laboratory recently developed a mouse model of transplacental induction of lymphoma, lung and liver cancer by the polycyclic aromatic hydrocarbon, dibenzo[a,l]pyrene (DBP). Pregnant B6129SF1 females, bred to 129S1/SvIm males, were treated on day 17 of gestation with an oral dose of 15 mg/kg DBP....

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Detalhes bibliográficos
Main Authors: Castro, David J., Yu, Zhen, Löhr, Christiane V., Pereira, Clifford B., Giovanini, Jack N., Fischer, Kay A., Orner, Gayle A., Dashwood, Roderick H., Williams, David E.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2516488/
https://ncbi.nlm.nih.gov/pubmed/18635525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgm237
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