Dibenzo[def,p]chrysene Transplacental Carcinogenesis in Wild-Type, Cyp1b1 Knockout and CYP1B1 Humanized Mice

The cytochrome P450 (CYP) 1 family is active toward numerous environmental pollutants, including polycyclic aromatic hydrocarbons (PAHs). Utilizing a mouse model, null for Cyp1b1 and expressing human CYP1B1, we tested the hypothesis that hCYP1B1 is important for dibenzo[def,p]chrysene (DBC) transpla...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Mol Carcinog
Auteurs principaux: Madeen, Erin P., Löhr, Christiane V., You, Hannah, Siddens, Lisbeth K., Krueger, Sharon K., Dashwood, Roderick H., Gonzalez, Frank J., Baird, William M., Ho, Emily, Bramer, Lisa, Waters, Katrina M., Williams, David E.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5457169/
https://ncbi.nlm.nih.gov/pubmed/26990437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22480
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires