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Synthesis of Prolinal Dithioacetals as Catalysts for the Highly Stereoselective Michael Addition of Ketones and Aldehydes to β-Nitrostyrenes

Catalytic highly enantioselective (up to >99% ee) and diastereoselective (up to 99% de) direct Michael addition of ketones and aldehydes to β-nitrostyrenes have been achieved with readily accessible and highly tunable prolinal dithioacetal catalysts.

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Detalhes bibliográficos
Main Authors: Mandal, Tanmay, Zhao, Cong-Gui
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2516343/
https://ncbi.nlm.nih.gov/pubmed/18704203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2007.06.085
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