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Excessive genomic DNA copy number variation in the Li–Fraumeni cancer predisposition syndrome

DNA copy number variations (CNVs) are a significant and ubiquitous source of inherited human genetic variation. However, the importance of CNVs to cancer susceptibility and tumor progression has not yet been explored. Li–Fraumeni syndrome (LFS) is an autosomal dominantly inherited disorder character...

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書誌詳細
主要な著者: Shlien, Adam, Tabori, Uri, Marshall, Christian R., Pienkowska, Malgorzata, Feuk, Lars, Novokmet, Ana, Nanda, Sonia, Druker, Harriet, Scherer, Stephen W., Malkin, David
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2516272/
https://ncbi.nlm.nih.gov/pubmed/18685109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802970105
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