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Excessive genomic DNA copy number variation in the Li–Fraumeni cancer predisposition syndrome
DNA copy number variations (CNVs) are a significant and ubiquitous source of inherited human genetic variation. However, the importance of CNVs to cancer susceptibility and tumor progression has not yet been explored. Li–Fraumeni syndrome (LFS) is an autosomal dominantly inherited disorder character...
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| Päätekijät: | , , , , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
National Academy of Sciences
2008
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2516272/ https://ncbi.nlm.nih.gov/pubmed/18685109 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802970105 |
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