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Excessive genomic DNA copy number variation in the Li–Fraumeni cancer predisposition syndrome
DNA copy number variations (CNVs) are a significant and ubiquitous source of inherited human genetic variation. However, the importance of CNVs to cancer susceptibility and tumor progression has not yet been explored. Li–Fraumeni syndrome (LFS) is an autosomal dominantly inherited disorder character...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2008
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2516272/ https://ncbi.nlm.nih.gov/pubmed/18685109 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802970105 |
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