RAPID CLONING OF HIGH AFFINITY HUMAN MONOCLONAL ANTIBODIES AGAINST INFLUENZA VIRUS

Pre-existing neutralizing antibody provides the first line of defense against pathogens in general. For influenza virus, annual vaccinations are given to maintain protective levels of antibody against the currently circulating strains. Here we report that after booster vaccination there was a rapid...

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Main Authors: Wrammert, Jens, Smith, Kenneth, Miller, Joe, Langley, Trey, Kokko, Kenneth, Larsen, Christian, Zheng, Nai-Ying, Mays, Israel, Garman, Lori, Helms, Christina, James, Judith, Air, Gillian M., Capra, J. Donald, Ahmed, Rafi, Wilson, Patrick C.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2515609/
https://ncbi.nlm.nih.gov/pubmed/18449194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature06890
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