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Atherosclerotic lesions and mitochondria DNA deletions in brain microvessels: Implication in the pathogenesis of Alzheimer’s disease

The pathogenesis that is primarily responsible for Alzheimer’s disease (AD) and cerebrovascular accidents (CVA) appears to involve chronic hypoperfusion. We studied the ultrastructural features of vascular lesions and mitochondria in brain vascular wall cells from human AD biopsy samples and two tra...

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Detalhes bibliográficos
Main Authors: Aliev, Gjumrakch, Gasimov, Eldar, Obrenovich, Mark E, Fischbach, Kathryn, Shenk, Justin C, Smith, Mark A, Perry, George
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2515433/
https://ncbi.nlm.nih.gov/pubmed/18827923
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