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Atherosclerotic lesions and mitochondria DNA deletions in brain microvessels: Implication in the pathogenesis of Alzheimer’s disease

The pathogenesis that is primarily responsible for Alzheimer’s disease (AD) and cerebrovascular accidents (CVA) appears to involve chronic hypoperfusion. We studied the ultrastructural features of vascular lesions and mitochondria in brain vascular wall cells from human AD biopsy samples and two tra...

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Bibliographische Detailangaben
Hauptverfasser: Aliev, Gjumrakch, Gasimov, Eldar, Obrenovich, Mark E, Fischbach, Kathryn, Shenk, Justin C, Smith, Mark A, Perry, George
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2008
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2515433/
https://ncbi.nlm.nih.gov/pubmed/18827923
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