The effect of acetyl-L-Carnitine and Lipoic acid treatment in ApoE4 mouse as a model of human Alzheimer’s disease

We measured age-dependent effects of the human ApoE4 on cerebral blood flow (CBF) using ApoE4 transgenic mice compared to age-matched wild-type (WT) mice by use of [(14)C] iodoantipyrene autoradiography. ApoE4 associated factors reduce CBF gradually to create brain hypoperfusion when compared to WT...

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Main Authors: Shenk, Justin C., Liu, Jiankang, Fischbach, Kathryn, Xu, Kui, Puchowicz, Michel, Obrenovich, Mark E., Gasimov, Eldar, Alvarez, Ludis Morales, Ames, Bruce N., LaManna, Joseph C., Aliev, Gjumrakch
Format: Artigo
Jezik:Inglês
Izdano: 2009
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2713369/
https://ncbi.nlm.nih.gov/pubmed/19342064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jns.2009.03.002
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