Neuronal mitochondrial amelioration by feeding acetyl-L-carnitine and lipoic acid to aged rats

Brain function declines with age and is associated with diminishing mitochondrial integrity. The neuronal mitochondrial ultrastructural changes of young (4 months) and old (21 months) F344 rats supplemented with two mitochondrial metabolites, acetyl-L-carnitine (ALCAR, 0.2%[wt/vol] in the drinking w...

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Detalhes bibliográficos
Main Authors: Aliev, Gjumrakch, Liu, Jiankang, Shenk, Justin C, Fischbach, Kathryn, Pacheco, Gerardo J, Chen, Shu G, Obrenovich, Mark E, Ward, Walter F, Richardson, Arlan G, Smith, Mark A, Gasimov, Eldar, Perry, George, Ames, Bruce N
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2009
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2790425/
https://ncbi.nlm.nih.gov/pubmed/18373733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2008.00324.x
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