Liposomal Packaging Generates Wnt Protein with In Vivo Biological Activity

Wnt signals exercise strong cell-biological and regenerative effects of considerable therapeutic value. There are, however, no specific Wnt agonists and no method for in vivo delivery of purified Wnt proteins. Wnts contain lipid adducts that are required for activity and we exploited this lipophilic...

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Detalhes bibliográficos
Main Authors: Morrell, Nathan T., Leucht, Philipp, Zhao, Ludan, Kim, Jae-Beom, ten Berge, Derk, Ponnusamy, Karthik, Carre, A. Lyonel, Dudek, Henryk, Zachlederova, Marie, McElhaney, Michael, Brunton, Shirley, Gunzner, Janet, Callow, Marinella, Polakis, Paul, Costa, Mike, Zhang, Xiaoyan M., Helms, Jill A., Nusse, Roel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2515347/
https://ncbi.nlm.nih.gov/pubmed/18698373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002930
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