t(8;21)(q22;q22) fusion proteins preferentially bind to duplicated AML1/RUNX1 DNA-binding sequences to differentially regulate gene expression

Eitemau Tebyg

• An update on the molecular pathogenesis and potential therapeutic targeting of AML with t(8;21)(q22;q22.1);RUNX1-RUNX1T1
  gan: Al-Harbi, Sayer, et al.
  Cyhoeddwyd: (2020)
• Acute myeloid leukemia with the 8q22;21q22 translocation: secondary mutational events and alternative t(8;21) transcripts
  gan: Peterson, Luke F., et al.
  Cyhoeddwyd: (2007)
• Histone deacetylase 3 preferentially binds and collaborates with the transcription factor RUNX1 to repress AML1–ETO–dependent transcription in t(8;21) AML
  gan: Guo, Chun, et al.
  Cyhoeddwyd: (2020)
• A Novel KIT INDEL Mutation in Acute Myeloid Leukemia With t(8;21)(q22;q22); RUNX1-RUNX1T1
  gan: Lee, Jun Hyung, et al.
  Cyhoeddwyd: (2016)
• The p21(Waf1) pathway is involved in blocking leukemogenesis by the t(8;21) fusion protein AML1-ETO
  gan: Peterson, Luke F., et al.
  Cyhoeddwyd: (2007)