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Distinct Effects on Splicing of Two Monoclonal Antibodies Directed against the Amino-terminal Domain of Galectin-3
Previous experiments had established that galectin-3 (Gal3) is a factor involved in cell-free splicing of pre-mRNA. Addition of monoclonal antibody NCL-GAL3, whose epitope maps to the NH(2)-terminal 14 amino acids of Gal3, to a splicing competent nuclear extract inhibited the splicing reaction. In c...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2515097/ https://ncbi.nlm.nih.gov/pubmed/18455493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2008.04.010 |
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