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Monoclonal Antibody-Directed Therapy

The book deals with therapeutic monoclonal antibodies (mAbs) broadly, and relevant topics such as challenges and opportunities, next-generation antibody products, Antibody-Drug-Conjugates (ADC), bispecifics, glycosylation, and T-cell engagers are covered. Each topic has been written by leading group...

Täydet tiedot

Tallennettuna:
Yhteisötekijät: Kayser, Veysel, Datta-Mannan, Amita
Aineistotyyppi: Livro
Kieli:Inglês
Julkaistu: MDPI - Multidisciplinary Digital Publishing Institute 2022
Aiheet:
thema EDItEUR::M Medicine and Nursing
thema EDItEUR::K Economics, Finance, Business and Management::KN Industry and industrial studies::KND Manufacturing industries
therapeutic antibody
stability
aggregation
manufacture challenges
formulation
antibodies
site-specific conjugation
bioconjugates
ADC
antibody-drug conjugates
payloads
linkers
nucleic acids
ADME
developability
glycosylation
post-translational modifications
pharmacokinetics
effector functions
antibody-dependent cell-mediated cytotoxicity
complement-dependent cytotoxicity
immunogenicity
pharmacodynamics
glycoengineering
type III secretion system
prophylaxis
antibacterials
antibiotics
HIV/AIDS
co-formulation
high concentration
analytical characterization
antibody (s)
T-cell engagers
bispecific antibodies
immunotherapy
oncology
antibody engineering
immunological synapse
Linkit:https://directory.doabooks.org/handle/20.500.12854/78804
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