Effects of mutations in poliovirus 3Dpol on RNA polymerase activity and on polyprotein cleavage.
A series of short insertion mutations was introduced into the poliovirus gene for 3Dpol at a number of different locations. When substituted for wild-type sequences in a full-length, infectious cDNA and tested for infectivity, all 3D mutants were nonviable. The mutant cDNAs were introduced into a ba...
Spremljeno u:
| Izdano u: | J Virol |
|---|---|
| Glavni autori: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology (ASM)
1989
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC251125/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2552159/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.63.11.4866-4874.1989 |
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