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Gliotoxin: inhibitor of poliovirus RNA synthesis that blocks the viral RNA polymerase 3Dpol.

The mode of action of gliotoxin against poliovirus has been analyzed in detail. This fungal metabolite inhibits the appearance of poliovirus proteins when present from the beginning of infection but has no effect on viral translation when added at late times. In agreement with previous findings, thi...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Rodriguez, P L, Carrasco, L
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1992
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288985/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1372367/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.4.1971-1976.1992
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