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Gliotoxin: inhibitor of poliovirus RNA synthesis that blocks the viral RNA polymerase 3Dpol.

The mode of action of gliotoxin against poliovirus has been analyzed in detail. This fungal metabolite inhibits the appearance of poliovirus proteins when present from the beginning of infection but has no effect on viral translation when added at late times. In agreement with previous findings, thi...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Rodriguez, P L, Carrasco, L
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288985/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1372367/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.4.1971-1976.1992
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