Effects of mutations in poliovirus 3Dpol on RNA polymerase activity and on polyprotein cleavage.

A series of short insertion mutations was introduced into the poliovirus gene for 3Dpol at a number of different locations. When substituted for wild-type sequences in a full-length, infectious cDNA and tested for infectivity, all 3D mutants were nonviable. The mutant cDNAs were introduced into a ba...

ver descrição completa

Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Burns, C C, Lawson, M A, Semler, B L, Ehrenfeld, E
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1989
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC251125/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2552159/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.63.11.4866-4874.1989
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!