Characterization of in vitro inhibition of human immunodeficiency virus by purified recombinant CD4.

The first step in infection of human T cells with human immunodeficiency virus (HIV) is binding of viral envelope glycoprotein gp120 to its cellular receptor, CD4. The specificity of this interaction has led to the development of soluble recombinant CD4 (rCD4) as a potential antiviral and therapeuti...

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Pubblicato in:	J Virol
Autori principali:	Byrn, R A, Sekigawa, I, Chamow, S M, Johnson, J S, Gregory, T J, Capon, D J, Groopman, J E
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1989
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC251054/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2550671/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.63.10.4370-4375.1989
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