Characterization of in vitro inhibition of human immunodeficiency virus by purified recombinant CD4.

The first step in infection of human T cells with human immunodeficiency virus (HIV) is binding of viral envelope glycoprotein gp120 to its cellular receptor, CD4. The specificity of this interaction has led to the development of soluble recombinant CD4 (rCD4) as a potential antiviral and therapeuti...

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Veröffentlicht in:	J Virol
Hauptverfasser:	Byrn, R A, Sekigawa, I, Chamow, S M, Johnson, J S, Gregory, T J, Capon, D J, Groopman, J E
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1989
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC251054/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2550671/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.63.10.4370-4375.1989
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