Characterization of in vitro inhibition of human immunodeficiency virus by purified recombinant CD4.

The first step in infection of human T cells with human immunodeficiency virus (HIV) is binding of viral envelope glycoprotein gp120 to its cellular receptor, CD4. The specificity of this interaction has led to the development of soluble recombinant CD4 (rCD4) as a potential antiviral and therapeuti...

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Bibliographic Details
Main Authors: Byrn, R A, Sekigawa, I, Chamow, S M, Johnson, J S, Gregory, T J, Capon, D J, Groopman, J E
Format: Artigo
Language:Inglês
Published: 1989
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC251054/
https://ncbi.nlm.nih.gov/pubmed/2550671
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