Hypertension, cardiac hypertrophy, and sudden death in mice lacking natriuretic peptide receptor A

Natriuretic peptides, produced in the heart, bind to the natriuretic peptide receptor A (NPRA) and cause vasodilation and natriuresis important in the regulation of blood pressure. We here report that mice lacking a functional Npr1 gene coding for NPRA have elevated blood pressures and hearts exhibi...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Oliver, Paula M., Fox, Jennifer E., Kim, Ron, Rockman, Howard A., Kim, Hyung-Suk, Reddick, Robert L., Pandey, Kailash N., Milgram, Sharon L., Smithies, Oliver, Maeda, Nobuyo
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1997
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC25105/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9405681/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.26.14730
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