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α-5/α-3 nicotinic receptor subunit alleles increase risk for heavy smoking

Twin studies indicate that additive genetic effects explain most of the variance in nicotine dependence (ND), a construct emphasizing habitual heavy smoking despite adverse consequences, tolerance and withdrawal. To detect ND alleles, we assessed cigarettes per day (CPD) regularly smoked, in two Eur...

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Hlavní autoři: Berrettini, W, Yuan, X, Tozzi, F, Song, K, Francks, C, Chilcoat, H, Waterworth, D, Muglia, P, Mooser, V
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2507863/
https://ncbi.nlm.nih.gov/pubmed/18227835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.mp.4002154
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