Genetic and molecular analyses of spontaneous mutants of human rhinovirus 14 that are resistant to an antiviral compound.

Spontaneous mutants of human rhinovirus 14 resistant to WIN 52084, an antiviral compound that inhibits attachment to cells, were isolated by selecting plaques that developed when wild-type virus was plated in the presence of high (2 micrograms/ml) or low (0.1 to 0.4 micrograms/ml) concentrations of...

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Main Authors: Heinz, B A, Rueckert, R R, Shepard, D A, Dutko, F J, McKinlay, M A, Fancher, M, Rossmann, M G, Badger, J, Smith, T J
Format: Artigo
Sprog:Inglês
Udgivet: 1989
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC250706/
https://ncbi.nlm.nih.gov/pubmed/2542566
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