Genetic and molecular analyses of spontaneous mutants of human rhinovirus 14 that are resistant to an antiviral compound.

Spontaneous mutants of human rhinovirus 14 resistant to WIN 52084, an antiviral compound that inhibits attachment to cells, were isolated by selecting plaques that developed when wild-type virus was plated in the presence of high (2 micrograms/ml) or low (0.1 to 0.4 micrograms/ml) concentrations of...

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Veröffentlicht in:	J Virol
Hauptverfasser:	Heinz, B A, Rueckert, R R, Shepard, D A, Dutko, F J, McKinlay, M A, Fancher, M, Rossmann, M G, Badger, J, Smith, T J
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1989
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC250706/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2542566/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.63.6.2476-2485.1989
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