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Yersinia enterocolitica induces apoptosis in macrophages by a process requiring functional type III secretion and translocation mechanisms and involving YopP, presumably acting as an effector protein

Yersiniae, causative agents of plague and gastrointestinal diseases, secrete and translocate Yop effector proteins into the cytosol of macrophages, leading to disruption of host defense mechanisms. It is shown in this report that Yersinia enterocolitica induces apoptosis in macrophages and that this...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Mills, Scott D., Boland, Anne, Sory, Marie-Paule, van der Smissen, Patrick, Kerbourch, Corinne, Finlay, B. Brett, Cornelis, Guy R.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1997
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC25065/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9356502/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.23.12638
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