Arginine-143 of Yersinia enterocolitica YopP Crucially Determines Isotype-Related NF-κB Suppression and Apoptosis Induction in Macrophages

Pathogenic Yersinia spp. counteract host defense mechanisms by modulating the cellular signal relay in response to infection. Subversion of the antiapoptotic NF-κB signaling pathway by the Yersinia enterocolitica virulence protein YopP crucially determines the induction of apoptosis in Yersinia-infe...

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Detalhes bibliográficos
Main Authors: Ruckdeschel, Klaus, Richter, Kathleen, Mannel, Oliver, Heesemann, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC98859/
https://ncbi.nlm.nih.gov/pubmed/11705945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.12.7652-7662.2001
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