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A Novel Dwarfism with Gonadal Dysfunction Due to Loss-of-Function Allele of the Collagen Receptor Gene, Ddr2, in the Mouse

Smallie (slie), a spontaneous, autosomal-recessive mutation causes dwarfing and infertility in mice. The purpose of this study was to determine and characterize the underlying molecular genetic basis for its phenotype. The slie locus was mapped to chromosome 1, and fine-structure mapping narrowed th...

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Hlavní autoři: Kano, Kiyoshi, Marín de Evsikova, C., Young, James, Wnek, Christopher, Maddatu, Terry P., Nishina, Patsy M., Naggert, Jürgen K.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Endocrine Society 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2505327/
https://ncbi.nlm.nih.gov/pubmed/18483174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2007-0310
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