Transcriptome analysis reveals an unexpected role of a collagen tyrosine kinase receptor gene, Ddr2, as a regulator of ovarian function

Mice homozygous for the smallie (slie) mutation lack a collagen receptor, discoidin domain receptor 2 (DDR2), and are dwarfed and infertile due to peripheral dysregulation of the endocrine system of unknown etiology. We used a systems biology approach to identify biological networks affected by Ddr2...

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Detalhes bibliográficos
Main Authors: Matsumura, Hirokazu, Kano, Kiyoshi, de Evsikova, Caralina Marín, Young, James A., Nishina, Patsy M., Naggert, Jürgen K., Naito, Kunihiko
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765065/
https://ncbi.nlm.nih.gov/pubmed/19671659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00073.2009
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