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Bone biopsy derived marrow stromal elements rescue chronic lymphocytic leukemia B-cells from spontaneous and drug induced cell death and facilitates an “angiogenic switch”

A novel bone biopsy technique was used to generate a robust stromal cell system to study how stroma modulates CLL B-cell apoptosis and how the leukemic cell–stromal interaction influences secretion of vascular factors. Marrow stromal elements (MSE) rescued CLL B-cells from both spontaneous and drug...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Kay, Neil E., Shanafelt, Tait D., Strege, Ann K., Lee, Yean K., Bone, Nancy D., Raza, Azra
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2007
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2505044/
https://ncbi.nlm.nih.gov/pubmed/17241660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2006.11.024
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