Platelet-derived growth factor (PDGF)–PDGF receptor interaction activates bone marrow–derived mesenchymal stromal cells derived from chronic lymphocytic leukemia: implications for an angiogenic switch

Malignant cells are capable of influencing the microenvironment in a manner that facilitates tumor cell survival. Bidirectional crosstalk between chronic lymphocytic leukemic (CLL) cells and marrow-derived mesenchymal stromal cells (MSCs) activates both cell types. In this study, we observed that th...

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Autores principales: Ding, Wei, Knox, Traci R., Tschumper, Renee C., Wu, Wenting, Schwager, Susan M., Boysen, Justin C., Jelinek, Diane F., Kay, Neil E.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2010
Materias:
Lymphoid Neoplasia
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2974606/
https://ncbi.nlm.nih.gov/pubmed/20606160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-02-269894
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