LEF-1 is a prosurvival factor in chronic lymphocytic leukemia and is expressed in the preleukemic state of monoclonal B-cell lymphocytosis

The canonical Wnt signaling pathway is pathogenic in a variety of cancers. We previously identified aberrant expression of the Wnt pathway transcription factor and target gene lymphoid enhancer binding factor-1 (LEF1) in chronic lymphocytic leukemia (CLL). This suggested that the Wnt signaling pathw...

Full description

Saved in:
Bibliographic Details
Main Authors: Gutierrez, Albert, Tschumper, Renee C., Wu, Xiaosheng, Shanafelt, Tait D., Eckel-Passow, Jeanette, Huddleston, Paul M., Slager, Susan L., Kay, Neil E., Jelinek, Diane F.
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2010
Subjects:
Lymphoid Neoplasia
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2974605/
https://ncbi.nlm.nih.gov/pubmed/20595513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-02-269878
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items