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Adaptive mutations in the signal peptide of the type 1 fimbrial adhesin of uropathogenic Escherichia coli

Signal peptides (SPs) are critical for protein transport across cellular membranes, have a highly conserved structure, and are cleaved from the mature protein upon translocation. Here, we report that naturally occurring mutations in the SP of the adhesive, tip-associated subunit of type 1 fimbriae (...

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Bibliographic Details
Main Authors: Ronald, Leah S., Yakovenko, Olga, Yazvenko, Nina, Chattopadhyay, Sujay, Aprikian, Pavel, Thomas, Wendy E., Sokurenko, Evgeni V.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2504816/
https://ncbi.nlm.nih.gov/pubmed/18664574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803158105
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