Comparative Structure-Function Analysis of Mannose-Specific FimH Adhesins from Klebsiella pneumoniae and Escherichia coli

FimH, the adhesive subunit of type 1 fimbriae expressed by many enterobacteria, mediates mannose-sensitive binding to target host cells. At the same time, fine receptor-structural specificities of FimH from different species can be substantially different, affecting bacterial tissue tropism and, as...

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Autores principales: Stahlhut, Steen G., Tchesnokova, Veronika, Struve, Carsten, Weissman, Scott J., Chattopadhyay, Sujay, Yakovenko, Olga, Aprikian, Pavel, Sokurenko, Evgeni V., Krogfelt, Karen Angeliki
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2009
Materias:
Molecular Biology of Pathogens
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795292/
https://ncbi.nlm.nih.gov/pubmed/19734306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00786-09
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