Differential Stability and Trade-Off Effects of Pathoadaptive Mutations in the Escherichia coli FimH Adhesin

FimH is the tip adhesin of mannose-specific type 1 fimbriae of Escherichia coli, which are critical to the pathogenesis of urinary tract infections. Point FimH mutations increasing monomannose (1M)-specific uroepithelial adhesion are commonly found in uropathogenic strains of E. coli. Here, we demon...

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Detaylı Bibliyografya
Asıl Yazarlar: Weissman, Scott J., Beskhlebnaya, Viktoriya, Chesnokova, Veronika, Chattopadhyay, Sujay, Stamm, Walter E., Hooton, Thomas M., Sokurenko, Evgeni V.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2007
Konular:
Bacterial Infections
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1932922/
https://ncbi.nlm.nih.gov/pubmed/17502398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01963-06
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