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Clonal analysis reveals high rate of structural mutations in fimbrial adhesins of extraintestinal pathogenic Escherichia coli

Type 1 fimbriae of Escherichia coli mediate mannose-specific adhesion to host epithelial surfaces and consist of a major, antigenically variable pilin subunit, FimA, and a minor, structurally conserved adhesive subunit, FimH, located on the fimbrial tip. We have analysed the variability of fimA and...

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Detalhes bibliográficos
Main Authors: Weissman, Scott J., Chattopadhyay, Sujay, Aprikian, Pavel, Obata-Yasuoka, Mana, Yarova-Yarovaya, Yuliya, Stapleton, Ann, Ba-Thein, William, Dykhuizen, Daniel, Johnson, James R., Sokurenko, Evgeni V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1380272/
https://ncbi.nlm.nih.gov/pubmed/16420365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2005.04985.x
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