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A pH-stabilizing role of voltage-gated proton channels in IgE-mediated activation of human basophils

Eosinophils and other phagocytes use NADPH oxidase to kill bacteria. Proton channels in human eosinophils and neutrophils are thought to sustain NADPH oxidase activity, and their opening is greatly enhanced by a variety of NADPH oxidase activators, including phorbol myristate acetate (PMA). In nonph...

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Autori principali: Musset, Boris, Morgan, Deri, Cherny, Vladimir V., MacGlashan, Donald W., Thomas, Larry L., Ríos, Eduardo, DeCoursey, Thomas E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2504794/
https://ncbi.nlm.nih.gov/pubmed/18664579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800886105
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