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Aspartate(112) is the Selectivity Filter of the Human Voltage Gated Proton Channel

The ion selectivity of pumps and channels is central to their ability to perform a multitude of functions. Here we investigate the mechanism of the extraordinary selectivity of the human voltage gated proton channel(1), hH(V)1. This selectivity is essential to its ability to regulate reactive oxygen...

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Detalhes bibliográficos
Main Authors: Musset, Boris, Smith, Susan M.E., Rajan, Sindhu, Morgan, Deri, Cherny, Vladimir V., DeCoursey, Thomas E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3237871/
https://ncbi.nlm.nih.gov/pubmed/22020278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10557
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