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A pH-stabilizing role of voltage-gated proton channels in IgE-mediated activation of human basophils

Eosinophils and other phagocytes use NADPH oxidase to kill bacteria. Proton channels in human eosinophils and neutrophils are thought to sustain NADPH oxidase activity, and their opening is greatly enhanced by a variety of NADPH oxidase activators, including phorbol myristate acetate (PMA). In nonph...

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Detalhes bibliográficos
Main Authors: Musset, Boris, Morgan, Deri, Cherny, Vladimir V., MacGlashan, Donald W., Thomas, Larry L., Ríos, Eduardo, DeCoursey, Thomas E.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2504794/
https://ncbi.nlm.nih.gov/pubmed/18664579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800886105
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