An acutely and latently expressed herpes simplex virus 2 viral microRNA inhibits expression of ICP34.5, a viral neurovirulence factor

Latency-associated transcript (LAT) sequences regulate herpes simplex virus (HSV) latency and reactivation from sensory neurons. We found a HSV-2 LAT-related microRNA (miRNA) designated miR-I in transfected and infected cells in vitro and in acutely and latently infected ganglia of guinea pigs in vi...

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Bibliographic Details
Main Authors: Tang, Shuang, Bertke, Andrea S., Patel, Amita, Wang, Kening, Cohen, Jeffrey I., Krause, Philip R.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2008
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2504787/
https://ncbi.nlm.nih.gov/pubmed/18678906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0801845105
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