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Herpes Simplex Virus 2 Expresses a Novel Form of ICP34.5, a Major Viral Neurovirulence Factor, through Regulated Alternative Splicing

Herpes simplex virus 1 (HSV-1) and HSV-2, two closely related neurotropic human herpesviruses, achieve neurotropism through ICP34.5, a major viral neurovirulence factor. In this report, in addition to the full-length 38-kDa protein (ICP34.5α), we identified a 28-kDa novel form of ICP34.5 (ICP34.5β)...

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Bibliografiset tiedot
Päätekijät: Tang, Shuang, Guo, Nini, Patel, Amita, Krause, Philip R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3648131/
https://ncbi.nlm.nih.gov/pubmed/23487469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03500-12
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