Opioids inhibit endothelin-mediated DNA synthesis, phosphoinositide turnover, and Ca2+ mobilization in rat C6 glioma cells

Opioid agonists inhibit DNA synthesis in C6 rat glioma cells that express opioid receptors, induced by desipramine (DMI). This inhibition was not observed in cells that were not treated with DMI, and thus did not express opioid-binding sites. Endothelin, a known mitogen, increased thymidine incorpor...

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Main Authors: Barg, J, Belcheva, MM, Zimlichman, R, Levy, R, Saya, D, McHale, RJ, Johnson, FE, Coscia, CJ, Vogel, Z
格式: Artigo
語言:Inglês
出版: Society for Neuroscience 1994
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Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2504522/
https://ncbi.nlm.nih.gov/pubmed/7931548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.14-10-05858.1994
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