Inflammation, Insulin Resistance, and Diabetes—Mendelian Randomization Using CRP Haplotypes Points Upstream

BACKGROUND: Raised C-reactive protein (CRP) is a risk factor for type 2 diabetes. According to the Mendelian randomization method, the association is likely to be causal if genetic variants that affect CRP level are associated with markers of diabetes development and diabetes. Our objective was to e...

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Detalhes bibliográficos
Main Authors: Brunner, Eric J, Kivimäki, Mika, Witte, Daniel R, Lawlor, Debbie A, Smith, George Davey, Cooper, Jackie A, Miller, Michelle, Lowe, Gordon D. O, Rumley, Ann, Casas, Juan P, Shah, Tina, Humphries, Steve E, Hingorani, Aroon D, Marmot, Michael G, Timpson, Nicholas J, Kumari, Meena
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2504484/
https://ncbi.nlm.nih.gov/pubmed/18700811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0050155
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