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Single Nucleotide Polymorphism Genotyping by Nanoparticle-Enhanced SPR Imaging Measurements of Surface Ligation Reactions

A sensitive method for the analysis of single nucleotide polymorphisms (SNPs) in genomic DNA that utilizes nanoparticle-enhanced surface plasmon resonance imaging (SPRI) measurements of surface enzymatic ligation reactions on DNA microarrays is demonstrated. SNP identification was achieved by using...

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Detalhes bibliográficos
Main Authors: Li, Yuan, Wark, Alastair W., Lee, Hye Jin, Corn, Robert M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2504468/
https://ncbi.nlm.nih.gov/pubmed/16643008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac0600151
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