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Dual-allele dipstick assay for genotyping single nucleotide polymorphisms by primer extension reaction

We have developed a dry-reagent dipstick test for simultaneous visual detection of two alleles in single nucleotide polymorphisms (SNPs). The strip comprises two test zones and a control zone. Oligonucleotide-functionalized gold nanoparticles are used as reporters. PCR-amplified DNA that spans the i...

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Détails bibliographiques
Auteurs principaux: Konstantou, Jessica K, Ioannou, Penelope C, Christopoulos, Theodore K
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2985959/
https://ncbi.nlm.nih.gov/pubmed/18685560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2008.139
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